Peroneal Neuropathy: Waiting for the Other Foot to Drop

A "foot-drop" is a medical termcollected a series of 318 patients with peroneal
which--thankfully--does not mean that the footneuropathy who required surgery, while Italian
suddenly disconnects from the leg. Rather, it meansresearchers collected another 69 cases that included
that when the leg is lifted from the ground, the footthose who didn't need surgery. From these two
droops downward at the ankle. The muscles that aretabulations of cases a good picture emerges of the
supposed to prop up the foot have become somore common causes of peroneal neuropathy.Many
weakened that they cannot overcome gravity'swere due to physical traumas. Some of the traumas
downward pull. When people with this problem try towere severe enough to break or dislocate bones,
walk, they have to either hike the leg higher to clearwhile others involved deep cuts in the soft tissues,
their drooping toes or else risk tripping overand still others involved just a stretch or bruise.
them.What is to blame for this inconvenientAnother common cause was surgical operations.
symptom? In truth, there are multiple possibleSome of the surgeries were to the nearby knee, but
causes, but one of the most common culprits isothers were performed on more distant structures,
injury to a nerve-bundle in the leg known as thelike the hip, the abdomen or even the chest.Many
peroneal nerve. To understand how this nerve-bundlecases were due to excessive external pressure being
can get in trouble, a quick review of the bones ofapplied to the nerve. This occurred in different ways.
the leg is helpful. There is just one bone, a big one,For example, in prolonged leg-crossing the knee of
that connects the hip to the knee, and that is thethe bottom leg pushes steadily against the peroneal
femur. There are two bones that connect the kneenerve of the crossing leg. Peroneal neuropathies seen
to the ankle. The tibia is the larger one and lies morein bedridden patients were presumably due to lying
to the inside, while the fibula is the thinner one andon the fibular tunnel for too long without a shift in
lies more to the outside. That's the extent of theposition. Other patients had entrapment or pinching of
bony anatomy we need to know.The nerve-fibersthe nerve within the fibular tunnel unrelated to
constituting the peroneal nerve travel with the hugeexternal pressure.A surprisingly large group of
sciatic nerve that runs behind the femur from thepatients had peroneal neuropathy due to weight loss,
buttock to the lower thigh. That's where thealso known as "slimmer's paralysis." More than one
"common peroneal nerve" splits out from the packfactor might have been at play in these cases,
and runs along the outside of the knee, tuckingincluding lack of nutrients, pressure on the nerve, or
behind the head of the fibular bone (a knobbyboth.Researchers and clinicians find that in some
protrusion just beyond the knee) and then snakingpeople an apparently isolated peroneal neuropathy is
around the neck of the fibula just below its head.actually the leading edge of a more widespread
The neck of the fibula forms the floor of the fibularpolyneuropathy. "Polyneuropathy" means that
tunnel that the common peroneal nerve must passperipheral nerves are impaired in a more diffuse
through. Within this tunnel the common peronealpattern--not just single nerves in single places. So in
nerve is particularly vulnerable to injury.Also within thissome cases of apparent peroneal neuropathy further
tunnel the common peroneal nerve splits into twoinvestigations turn up polyneuropathy due to other
branches, the "deep peroneal nerve" (farther fromcauses, for example, diabetes, excessive alcohol
the leg's surface) and the "superficial peroneal nerve"consumption or genetic factors.How are cases
(closer to the leg's surface). Because the twoevaluated? The physician's evaluation starts with the
branches have different connections to muscles andtime-honored methods of history-taking and physical
skin, injury to one produces different impairmentsexamination. As part of the physical examination the
than are produced by injury to the other.The deepdoctor inventories which muscles are weak (and
peroneal nerve is responsible for cocking up the anklewhich are not) and maps out areas of numbness
and toes, so injury to this branch produces weaknessaffecting the skin. Additional testing with
or paralysis of the muscles responsible for theseelectromyography and nerve conduction studies,
actions. There is just a tiny patch of skin, locatedwhich check on electrical functions of the muscles
between the big toe and the toe next to it,and nerves, often provides valuable information,
connected to the deep peroneal nerve, so damageincluding whether additional nerves are affected and
to this branch produces numbness limited to this smallhow bad the impairments are.How about treatment?
area.The superficial peroneal nerve, by contrast, isTreatment varies according to what caused the
responsible for skin sensation on most of the outsideperoneal neuropathy in the first place, but let's
of the calf and top of the foot, so these areas canconsider a typical case unrelated to severe trauma.
become numb when the superficial peroneal nerve isNonsurgical approaches are usually tried first, including
injured. This branch is also responsible for lifting theavoidance of further pressure on the peroneal nerve,
outside edge of the foot, so this action is gone whenimproved nutrition and supplementation of the diet
the superficial peroneal nerve is not functioningwith vitamins. A simple brace applied to the ankle
properly.Impairments due to injury of the commonimproves walking. In many cases the nerve recovers
peroneal nerve (the parent of the two branches) arewithout anything more drastic being done. But if
the sum of the impairments associated with each ofthese conservative treatments fail (and the peroneal
the branches. So this means that the ankle and toesneuropathy is not part of a more widespread
cannot cock upwards, the outside edge of the footpolyneuropathy) then surgical exploration of the
cannot lift, and there is numbness on the outside offibular tunnel is often indicated. If the nerve is
the calf and top of the foot."Peroneal neuropathy"pinched, then the surgeon frees up the nerve from
means impairment of the peroneal nerve. Peronealwhatever was pinching it.(C) 2005 by Gary
neuropathies are the most common neuropathies (ofCordingleyGary Cordingley, MD, PhD, is a clinical
the kind that affects just one nerve at a time) in theneurologist, teacher and researcher who works in
lower extremities. Investigators at the LouisianaAthens, Ohio.
State University Health Sciences Center recently